[Noncardiogenic pulmonary edema in the course of poisoning with clozapine, ketoprofen and thiethylperazine]. / Niekardiogenny obrzek pluc w przebiegu zatrucia klozapina, ketoprofenem i tietylperazyna.

Pulmonary edema is a severe, potentially fatal clinical condition. It happens, when interstitial fluid is accumulating in the alveoli, impeding proper gas exchange. Typically we distinguish cardiogenic and noncardiogenic pulmonary edema. The article describes the case of severe pulmonary edema, which occurred in a young woman, free of cardiac diseases, about 30 hours after a suicidal drug poisoning (clozapine, ketoprofen, thiethylperazine). Both clozapine and ketoprofen intoxication, may be severe. Complications in these poisonings affect not only the central nervous system, but also the circulatory or respiratory system and may even occur several hours after the overdose of these drugs. The study considered the causes and possible mechanisms of pulmonary edema in poisoning with these drugs.

[A severe dystonic reaction in acute Torecan poisoning]. / Reactie distonica severa în intoxicatia acuta cu Torecan.

Phenothiazines are a widely used group of drugs for medical practice. Some of them, including Torecan, may induce dystonic reactions of severe aspect which may lead to errors of diagnosis. Although in the paediatric practice this drug is but seldom used the possibility of intoxications exists when it is used without a medical prescription. The authors present two cases where neurological manifestations occurred, as severe, dystonic phenomena, that had a favourable evolution, under adequate therapy.